Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS III |
| Enrichment Score (ES) | -0.8980938 |
| Normalized Enrichment Score (NES) | -1.7025769 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0080583645 |
| FWER p-Value | 0.035 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | BAX | 17832 | 1000 | 0.840 | -0.0274 | No | ||
| 2 | XRCC6 | 2286 8991 | 2190 | 0.294 | -0.0822 | No | ||
| 3 | SIRT3 | 17569 3713 | 3877 | 0.045 | -0.1715 | No | ||
| 4 | HOXA10 | 17145 989 | 4684 | 0.025 | -0.2141 | No | ||
| 5 | FOXO3 | 19782 3402 | 10282 | -0.001 | -0.5152 | No | ||
| 6 | FHL2 | 13966 | 10533 | -0.001 | -0.5286 | No | ||
| 7 | TUBB2A | 21493 | 11571 | -0.004 | -0.5842 | No | ||
| 8 | ACSS2 | 12242 2684 | 11931 | -0.005 | -0.6034 | No | ||
| 9 | HIST1H1E | 21520 | 12332 | -0.007 | -0.6247 | No | ||
| 10 | MYOD1 | 18237 | 12758 | -0.009 | -0.6473 | No | ||
| 11 | MEF2D | 9379 | 15725 | -0.101 | -0.8037 | No | ||
| 12 | PPARGC1A | 16533 | 15834 | -0.119 | -0.8058 | No | ||
| 13 | SIRT2 | 18318 | 16994 | -0.442 | -0.8543 | No | ||
| 14 | SIRT1 | 19745 | 17091 | -0.483 | -0.8443 | No | ||
| 15 | HIST1H4B | 6820 | 18092 | -1.222 | -0.8598 | Yes | ||
| 16 | CREBBP | 22682 8783 | 18124 | -1.271 | -0.8216 | Yes | ||
| 17 | SIRT7 | 9923 | 18145 | -1.304 | -0.7818 | Yes | ||
| 18 | HIST2H4A | 15240 | 18179 | -1.355 | -0.7411 | Yes | ||
| 19 | HIST1H4D | 11410 | 18217 | -1.418 | -0.6986 | Yes | ||
| 20 | HIST1H4C | 6643 | 18262 | -1.537 | -0.6528 | Yes | ||
| 21 | ACSS1 | 12729 | 18292 | -1.626 | -0.6034 | Yes | ||
| 22 | HIST1H4I | 6645 | 18351 | -1.769 | -0.5510 | Yes | ||
| 23 | HIST1H4F | 6644 | 18380 | -1.867 | -0.4940 | Yes | ||
| 24 | CDKN1A | 4511 8729 | 18388 | -1.909 | -0.4345 | Yes | ||
| 25 | HIST1H4J | 11411 | 18389 | -1.913 | -0.3745 | Yes | ||
| 26 | HIST1H4K | 11412 | 18402 | -1.944 | -0.3142 | Yes | ||
| 27 | HIST1H4A | 11590 | 18429 | -2.050 | -0.2513 | Yes | ||
| 28 | HIST1H4H | 7618 | 18438 | -2.095 | -0.1860 | Yes | ||
| 29 | HIST4H4 | 6747 | 18472 | -2.326 | -0.1149 | Yes | ||
| 30 | TP53 | 20822 | 18582 | -3.909 | 0.0018 | Yes |
